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ORIGINAL ARTICLE
Year : 2016  |  Volume : 18  |  Issue : 2  |  Page : 119-125

“To Assess the Clinical Profile and Risk Factors Associated with Myocardial Infarction In Young Adults”


1 Resident, Department of General Medicine, INHS Asvini, Mumbai, India
2 HOD (Medicine and GE) INHS Asvini, Mumbai, India

Correspondence Address:
Chandrashekhar Yadav
Resident, Department of General Medicine, INHS Asvini, Mumbai
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0975-3605.204462

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Background: The Global Burden of Diseases (GBD) study reported the estimated mortality from CAD in India at 1.6 million in the year 2000. It has been predicted that by the year 2020 there will be an increase by almost 75% in the global CVD burden. Acute MI in young adults is characterized by the presence of multiple risk factors which tend to be additive in influencing morbidity and mortality. A contributory factor, which may explain the abnormalities in lipid profile of Indians, is the high risk atherosclerotic diet, which promotes over nutrition, obesity and diabetes. Methods: It is an observational study done at tertiary care center. In our study we studied 55 consecutive patients suffered with acute myocardial Infarction (AMI) between age group 15-45 years, fulfilling inclusion criteria. We assessed clinical profile and their risk factors. Results:
  1. Mean age of acute myocardial infarction was 40.6 years.
  2. Ajority of the patients were male (94.5%) and between the age group of 41-45 years (50.9%), chest pain was commonest presentation.
  3. Smoking was the most common risk factor (61.8%), followed raised homocysteine level (45.5%). Family history of Premature CAD was presents in significant number of individuals (36.4%). Obesity with raised BMI was found in 10.9% patients. Incidence of DM was 18.2%, hypertension was seen in 10.9%cases. Abnormalities in lipidprofile were seen 21.8% patients. Hyperuricemia was found in 31 %, AB positive blood group was most common and was presents in 34.5%.
  4. In most individuals single blood vessel was involved (76.4%) with good left ventricular (LV) function (49%) and over all prognoses was good in patients with door to stent time less than 60 min. The coronary arteries involved in these cases were LAD in 36.4%, LCX in 20% and RCA in 20%.
Conclusion: In young MI cases conventional risk factors like diabetes mellitus, hypertension play less important role as compared to old individuals. Smoking and novel emerging risk factors like hyperhomocysteinemia, protein C & S deficiency play much prominent role in young patients with MI.


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